Can we predict lung failure in children by measuring their breathing effort?
NCT ID NCT07750288
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study investigates whether measuring the physical effort of breathing in children with acute respiratory distress syndrome (ARDS) can predict how the disease will progress. Researchers will use advanced, non-invasive monitoring tools to track breathing drive, effort, and lung aeration during key phases of treatment. The goal is to find thresholds that signal early deterioration, which could help doctors adjust breathing support more precisely and avoid further lung damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Advanced respiratory monitoring tools (surface electromyography, esophageal manometry, and electrical impedance tomography)
- What this could lead to
- If successful, this could lead to algorithms that help doctors adjust breathing support more safely in critically ill children, potentially preventing lung damage and improving outcomes.
- What could go wrong
- This is an observational study with a small number of participants, so the findings may not apply to all children. The measurements are complex and may not reliably predict outcomes in real-world settings.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital El Carmen Dr. Luis Valentin Ferrada
RECRUITINGSantiago, Chile
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