New heartburn drug put to the test – with and without food
NCT ID NCT07364838
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tested a new drug called DW4421 in 24 healthy adults to see how food changes the way the body absorbs it. The goal is to learn whether the drug should be taken with or without food for future studies. This is a safety and dosing study, not a test of whether the drug works for GERD.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DW4421
What this could lead to
If successful, this could help develop a new medication for heartburn and acid reflux (GERD) that is taken with or without food.
What could go wrong
This is a very early Phase 1 trial in only 24 healthy people, not patients. It only tests how food affects the drug, not whether it works for GERD. Many drugs fail in later stages.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GERD (GASTROESOPHAGEAL REFLUX DISEASE) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Chungbuk National University Hospital
Cheongju-si, South Korea