New hope for lung cancer patients: immunotherapy after surgery may keep cancer away

NCT ID NCT06284317

Recruiting now Disease control Sponsor: ETOP IBCSG Partners Foundation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people with a certain type of lung cancer (stage IIB-IIIB) that can be removed with surgery. Participants first get chemotherapy plus the immunotherapy drug durvalumab before surgery. After surgery, those whose cancer did not fully disappear are randomly assigned to receive more durvalumab or just be watched. The goal is to see if extra durvalumab helps keep the cancer from returning.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER

Contacts and locations

Locations

AOUS Policlinico Le Scotte
NOT_YET_RECRUITING

Siena, Italy
Alfred Hospital
RECRUITING

Melbourne, Victoria, Australia
Antwerp University Hospital
RECRUITING

Antwerp, Belgium
Barts Health NHS Trust
RECRUITING

London, United Kingdom
Beaumont Hospital
RECRUITING

Dublin, Ireland
CHU Angers
RECRUITING

Angers, France
CHUV
NOT_YET_RECRUITING

Lausanne, Switzerland
Chris O'Brien Lifehouse
NOT_YET_RECRUITING

Camperdown, New South Wales, Australia
Eastern Health
RECRUITING

Box Hill, Victoria, Australia
Eoc - Iosi
NOT_YET_RECRUITING

Bellinzona, Switzerland
Flinders Medical Centre
NOT_YET_RECRUITING

Bedford Park, South Australia, Australia
HFR Hôpital Fribourgeois
RECRUITING

Fribourg, Switzerland
Inselspital Bern
RECRUITING

Bern, Switzerland
Institut Bergonié
RECRUITING

Bordeaux, France
Institut Jules Bordet - HUB
RECRUITING

Anderlecht, Belgium
Istituto Nazionale Tumori "Regina Elena"
RECRUITING

Rome, Italy
Istituto Oncologico Veneto
RECRUITING

Padova, Italy
Kantonsspital Baden
NOT_YET_RECRUITING

Baden, Switzerland
Kantonsspital St.Gallen
RECRUITING

Sankt Gallen, Switzerland
Kantonsspital Winterthur
RECRUITING

Winterthur, Switzerland
Le Mans - CHG
RECRUITING

Le Mans, France
Lyon - Centre Léon Bérard
RECRUITING

Lyon, France
Maidstone and Tunbridge Wells NHS Trust
RECRUITING

Maidstone, United Kingdom
NKI
RECRUITING

Amsterdam, Netherlands
Nepean Hospital
RECRUITING

Penrith, New South Wales, Australia
North Estonia Medical Centre Foundation
RECRUITING

Talinn, Estonia
Perugia Hospital
NOT_YET_RECRUITING

Perugia, Italy
Peter MacCallum Cancer Centre
RECRUITING

Parkville, Victoria, Australia
Princess Alexandra Hospital
NOT_YET_RECRUITING

Woolloongabba, Queensland, Australia
Royal Hobart Hospital
NOT_YET_RECRUITING

Hobart, Tasmania, Australia
Royal Marsden Hospital (Chelsea)
NOT_YET_RECRUITING

London, United Kingdom
Royal Marsden Hospital (Sutton)
NOT_YET_RECRUITING

London, United Kingdom
Royal North Shore Hospital
RECRUITING

St Leonards, New South Wales, Australia
SS Antonio e Biagio e Cesare Arrigo Hospital
NOT_YET_RECRUITING

Alessandria, Italy
Sir Charles Gairdner Hospital
NOT_YET_RECRUITING

Nedlands, Western Australia, Australia
St James's Hospital
RECRUITING

Dublin, Ireland
UMCU
RECRUITING

Utrecht, Netherlands
Universita di Verona - Department of Medicine
RECRUITING

Verona, Italy
University Hospital Zurich
NOT_YET_RECRUITING

Zurich, Switzerland
Universitätsspital Basel
RECRUITING

Basel, Switzerland
Wien AKH
RECRUITING

Vienna, Austria
Wythenshawe Hospital, Manchester University NHS Foundation Trust
RECRUITING

Manchester, United Kingdom

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