New drug cocktail shows promise for aggressive breast cancer

NCT ID NCT03742102

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 25 times

Summary

This study tests whether combining the immunotherapy drug durvalumab with other cancer treatments (with or without chemotherapy) can help control metastatic triple-negative breast cancer in people who haven't had prior treatment for advanced disease. About 243 women with advanced or metastatic TNBC will receive different drug combinations to see how well they work and what side effects occur. The goal is to shrink tumors and delay progression, not to cure the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Tucson, Arizona, 85715, United States

  • Research Site

    Columbia, Maryland, 21044, United States

  • Research Site

    Boston, Massachusetts, 02114, United States

  • Research Site

    Boston, Massachusetts, 02215, United States

  • Research Site

    Grand Rapids, Michigan, 49503, United States

  • Research Site

    St Louis, Missouri, 63110, United States

  • Research Site

    Dallas, Texas, 75246, United States

  • Research Site

    Williamsburg, Virginia, 23188, United States

  • Research Site

    Kelowna, British Columbia, V1Y 5L3, Canada

  • Research Site

    London, Ontario, N6A 4L6, Canada

  • Research Site

    Greenfield Park, Quebec, J4V 2H1, Canada

  • Research Site

    Montreal, Quebec, H4A 3J1, Canada

  • Research Site

    Gdansk, 80-952, Poland

  • Research Site

    Krakow, 31-501, Poland

  • Research Site

    Lublin, 20-090, Poland

  • Research Site

    Opole, 45-060, Poland

  • Research Site

    Rzeszów, 35-021, Poland

  • Research Site

    Warsaw, 02-781, Poland

  • Research Site

    Warsaw, 04-141, Poland

  • Research Site

    Seoul, 03080, South Korea

  • Research Site

    Seoul, 05505, South Korea

  • Research Site

    Seoul, 06351, South Korea

  • Research Site

    Kaohsiung City, 80756, Taiwan

  • Research Site

    Taichung, 40447, Taiwan

  • Research Site

    Tainan, 70403, Taiwan

  • Research Site

    Taipei, 10002, Taiwan

  • Research Site

    Taipei, 112, Taiwan

  • Research Site

    Taoyuan, 333, Taiwan

  • Research Site

    Cambridge, CB2 0QQ, United Kingdom

  • Research Site

    London, EC1M 6BQ, United Kingdom

  • Research Site

    Manchester, M20 4BX, United Kingdom

  • Research Site

    Oxford, OX3 7LE, United Kingdom

Conditions

Explore the condition pages connected to this study.