Cure My Disease

Don't miss your cure!

 Log in / Sign up

Mesh-Like suture could cut hernia risk after cancer surgery

NCT ID NCT07683546

Disease control Sponsor: Aristotle University Of Thessaloniki Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This trial tests whether a special mesh-like suture (Duramesh) can prevent incisional hernias better than a standard slowly-absorbable suture (PDS loop) in women having abdominal surgery for gynecological cancers. About 300 participants will be randomly assigned to one of the two closure methods. The study tracks hernia occurrence, wound healing, and pain for up to one year after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Duramesh (mesh suture) and PDS II 1-0 double loop suture
What this could lead to
If Duramesh works better, it could reduce the number of women who develop a hernia after major abdominal surgery for gynecological cancer.
What could go wrong
This is a single-center trial, so results may not apply to all hospitals. The mesh suture might also increase the risk of infection or other wound problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Mar 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Midline laparotomies for gynecological malignancies * Age 18 - 85 years old * ECOG Performance status: 0 - 2 Exclusion Criteria: * Pregnancy * Albumin \< 3.5 g/dL * Previous history of any type of hernia * Previous midline incision (via laparotomy)

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Duramesh are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

female reproductive organ cancer Incisional Hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Duramesh Hernia incisional Suture materials

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.