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Can lung cancer patients skip brain radiation? new trial explores alectinib alone first.

NCT ID NCT05987644

Recruiting now Disease control Sponsor: Joshua Palmer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether people with lung cancer that has spread to the brain can safely delay radiation therapy. Participants take alectinib, a targeted drug, either alone or with focused radiation. The goal is to see if starting with just the drug keeps the brain cancer under control and avoids side effects from radiation. The trial is for patients with few or no symptoms from their brain tumors.

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Conditions

The condition(s) this trial relates to.

brain cancer lung cancer lung neoplasm metastatic malignant neoplasm in the brain non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN METASTASES LUNG CANCER NSCLC

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Email: •••••@•••••

    Contact

  • Stanford University

    RECRUITING

    Stanford, California, 94305, United States

    Contact Email: •••••@•••••

    Contact

  • University of Colorado Cancer Center

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Email: •••••@•••••

More trials for these conditions

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