Which treatment works best for Dupuytren's? major trial aims to find out
NCT ID NCT03192020
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares three treatments for Dupuytren's contracture, a hand condition that causes fingers to bend inward. The treatments are needle fasciotomy (a quick in-office procedure), collagenase injection (a drug that breaks up the tight cord), and surgery (limited fasciectomy). The trial involves 302 adults with at least 20 degrees of finger bending. The goal is to see which approach is most cost-effective and provides the best long-term results.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Collagenase Clostridium Histolyticum (CCH) injection
What this could lead to
If this trial succeeds, it could identify the most effective and cost-efficient treatment for Dupuytren's contracture, helping patients and doctors choose the best option.
What could go wrong
This is a phase 4 trial, but results are still pending. The best treatment may depend on individual patient factors, and not all patients may respond equally to each approach.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DUPUYTREN CONTRACTURE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Central Hospital of Central Finland
Jyväskylä, Central Finland, 40620, Finland
-
Helsinki University hospital
Helsinki, Uusimaa, 00029, Finland
-
Kuopio University hospital
Kuopio, Northern Savonia, 70029, Finland
-
Oulu University hospital
Oulu, North Ostrobothnia, 90220, Finland
-
Tampere University Hospital
Tampere, Pirkanmaa, 33521, Finland
-
Turku University Hospital
Turku, Southwest Finland, 20521, Finland