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Real-World dupixent: does it live up to the hype for eczema?

NCT ID NCT03992417

Ongoing Knowledge-focused Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study follows about 955 people aged 12 and older who are starting treatment with Dupixent (dupilumab) for atopic dermatitis, commonly known as eczema. The goal is to see how the drug performs in everyday clinical practice, not just in controlled trials. Researchers will track patients' medical history, treatment patterns, and long-term effectiveness, as well as any side effects. The findings could help doctors better understand who benefits most from Dupixent and how to use it optimally.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Dupilumab (Dupixent), an injectable biologic drug for atopic dermatitis
What this could lead to
If successful, this study could provide a clearer picture of how Dupixent performs in real-world settings, helping doctors tailor treatment for different patients.
What could go wrong
Because this is an observational study, it cannot prove cause and effect. Results may be influenced by factors like patient selection and adherence, and long-term safety data are still being collected.

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DERMATITIS ATOPIC

Contacts and locations

Locations

  • Investigational Site Number : 0320011

    Ciudad Autonoma Bs As, C1121ABE, Argentina

  • Investigational Site Number : 0320012

    Rosario, Santa Fe Province, S2000DBS, Argentina

  • Investigational Site Number : 0320013

    Pilar, Buenos Aires, B1629ODT, Argentina

  • Investigational Site Number : 0360001

    Carlton, Victoria, 3053, Australia

  • Investigational Site Number : 0360002

    Kogarah, New South Wales, 2217, Australia

  • Investigational Site Number : 0360003

    Woolloongabba, Queensland, 4102, Australia

  • Investigational Site Number : 0360004

    Bedford Park, South Australia, 5042, Australia

  • Investigational Site Number : 0360005

    Kogarah, New South Wales, 2217, Australia

  • Investigational Site Number : 0400001

    Vienna, 1220, Austria

  • Investigational Site Number : 0400002

    Maria Enzersdorf, 2344, Austria

  • Investigational Site Number : 0400004

    Linz, 4020, Austria

  • Investigational Site Number : 0400005

    Graz, 8036, Austria

  • Investigational Site Number : 0560001

    Leige, 4000, Belgium

  • Investigational Site Number : 0560002

    Brussels, 1200, Belgium

  • Investigational Site Number : 0560003

    Jette, 1090, Belgium

  • Investigational Site Number : 0560006

    Roeselare, 8800, Belgium

  • Investigational Site Number : 0560007

    Edegem, 2650, Belgium

  • Investigational Site Number : 0560008

    Leuven, 3000, Belgium

  • Investigational Site Number : 0560010

    Ghent, 9000, Belgium

  • Investigational Site Number : 1580011

    Taichung, 40201, Taiwan

  • Investigational Site Number : 1580012

    Kaohsiung City, 833401, Taiwan

  • Investigational Site Number : 1580014

    Taipei, 100, Taiwan

  • Investigational Site Number : 1580015

    Taoyuan County, 333, Taiwan

  • Investigational Site Number : 1700008

    Bogotá, 11001, Colombia

  • Investigational Site Number : 1700011

    Medellín, 050034, Colombia

  • Investigational Site Number : 1700012

    Bogotá, 110221, Colombia

  • Investigational Site Number : 2030001

    Ústí nad Labem, 40113, Czechia

  • Investigational Site Number : 2030002

    Prague, 150 06, Czechia

  • Investigational Site Number : 2030003

    Ostrava - Poruba, 70852, Czechia

  • Investigational Site Number : 2030004

    Pilsen, 304 60, Czechia

  • Investigational Site Number : 2030005

    Prague, 110 01, Czechia

  • Investigational Site Number : 2030006

    Olomouc, 77900, Czechia

  • Investigational Site Number : 2030008

    Hradec Králové, 50005, Czechia

  • Investigational Site Number : 2460002

    Kokkola, 67200, Finland

  • Investigational Site Number : 2500001

    Valence, 26953, France

  • Investigational Site Number : 2500002

    Toulouse, 31059, France

  • Investigational Site Number : 2500003

    Bordeaux, 33000, France

  • Investigational Site Number : 2500005

    Saint-Mandé Cedex, 94160, France

  • Investigational Site Number : 2500006

    Pierre-Bénite, 69495, France

  • Investigational Site Number : 2500009

    Montpellier, 34295, France

  • Investigational Site Number : 2500010

    Rouen, 76000, France

  • Investigational Site Number : 2500011

    Antony, 92160, France

  • Investigational Site Number : 3000001

    Thessaloniki, 56403, Greece

  • Investigational Site Number : 3000003

    Thessaloniki, 54645, Greece

  • Investigational Site Number : 3760001

    Haifa, 3109601, Israel

  • Investigational Site Number : 3760002

    Jerusalem, 91120, Israel

  • Investigational Site Number : 3760004

    Ramat Gan, 5266202, Israel

  • Investigational Site Number : 3760005

    Haifa, 31048, Israel

  • Investigational Site Number : 3760006

    Afula, 18101, Israel

  • Investigational Site Number : 3800001

    Naples, 80131, Italy

  • Investigational Site Number : 3800003

    Rome, Roma, 00133, Italy

  • Investigational Site Number : 3800004

    Milan, 20122, Italy

  • Investigational Site Number : 3800005

    Roma, 00137, Italy

  • Investigational Site Number : 3800007

    Brescia, 25123, Italy

  • Investigational Site Number : 3800008

    Genova, 16132, Italy

  • Investigational Site Number : 3800009

    Torrette Di Ancona, Ancona, 60126, Italy

  • Investigational Site Number : 3800010

    Pisa, 56126, Italy

  • Investigational Site Number : 3800011

    Rome, Roma, 00161, Italy

  • Investigational Site Number : 3800012

    Bari, 70124, Italy

  • Investigational Site Number : 3800013

    Cagliari, 09124, Italy

  • Investigational Site Number : 3800015

    L’Aquila, 67100, Italy

  • Investigational Site Number : 3800016

    Torino, 10126, Italy

  • Investigational Site Number : 3800017

    Terracina, Latina, 04019, Italy

  • Investigational Site Number : 3920001

    Nagoya, 454-8509, Japan

  • Investigational Site Number : 3920002

    Habikino-shi, 583-8588, Japan

  • Investigational Site Number : 3920003

    Itabashi-ku, Tokyo, 173-8606, Japan

  • Investigational Site Number : 3920004

    Nagakute-shi, Aichi-ken, 480-1195, Japan

  • Investigational Site Number : 3920005

    Shimotsuga-gun, Tochigi, 321-0293, Japan

  • Investigational Site Number : 3920006

    Sapporo, Hokkaido, 060-0807, Japan

  • Investigational Site Number : 3920008

    Koshigaya-shi, Saitama, 343-8555, Japan

  • Investigational Site Number : 3920010

    Setagaya-ku, 156-0043, Japan

  • Investigational Site Number : 3920011

    Hirakata-shi, Osaka, 573-1191, Japan

  • Investigational Site Number : 3920012

    Minokamo-shi, 505-8503, Japan

  • Investigational Site Number : 3920013

    Marugame-shi, 763-0074, Japan

  • Investigational Site Number : 3920014

    Hamamatsu, 430-0929, Japan

  • Investigational Site Number : 3920015

    Obihiro-shi, Hokkaido, 080-0013, Japan

  • Investigational Site Number : 3920020

    Yokohama, 234-8503, Japan

  • Investigational Site Number : 3920022

    Amagasaki-shi, 660-8550, Japan

  • Investigational Site Number : 3920025

    Kyoto, 604-8845, Japan

  • Investigational Site Number : 4140001

    Sulaibikat, 90806, Kuwait

  • Investigational Site Number : 4840001

    Guadalajara, Jalisco, 44130, Mexico

  • Investigational Site Number : 5280002

    Bergen op Zoom, 4624 VT, Netherlands

  • Investigational Site Number : 5780001

    Bodø, 8005, Norway

  • Investigational Site Number : 5780002

    Bergen, N-5021, Norway

  • Investigational Site Number : 6200001

    Vila Nova de Gaia, 4434-502, Portugal

  • Investigational Site Number : 6200002

    Lisbon, 1169-050, Portugal

  • Investigational Site Number : 6200003

    Coimbra, 3000-075, Portugal

  • Investigational Site Number : 6200004

    Porto, 4099-001, Portugal

  • Investigational Site Number : 6430001

    Moscow, 123182, Russia

  • Investigational Site Number : 6430004

    Saint Petersburg, 191015, Russia

  • Investigational Site Number : 6820013

    Dammam, 31444, Saudi Arabia

  • Investigational Site Number : 7240001

    Madrid, 28041, Spain

  • Investigational Site Number : 7240002

    Oviedo, Principality of Asturias, 33011, Spain

  • Investigational Site Number : 7240004

    Las Palmas de Gran Canaria, Las Palmas, 35010, Spain

  • Investigational Site Number : 7240006

    Madrid, 28034, Spain

  • Investigational Site Number : 7240007

    Madrid, 28031, Spain

  • Investigational Site Number : 7240008

    Santiago de Compostela, 15706, Spain

  • Investigational Site Number : 7240009

    Barcelona, 08041, Spain

  • Investigational Site Number : 7240010

    Madrid, 28040, Spain

  • Investigational Site Number : 7240012

    Majadahonda, Madrid, 28222, Spain

  • Investigational Site Number : 7240014

    Barcelona, Spain

  • Investigational Site Number : 7240016

    Madrid, 28006, Spain

  • Investigational Site Number : 7240017

    Barakaldo, 48903, Spain

  • Investigational Site Number : 7240019

    Bilbao, Bizkaia, 48013, Spain

  • Investigational Site Number : 7840002

    Abu Dhabi, 34761, United Arab Emirates

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