Double-Drug attack: new hope for tough Crohn's cases?

NCT ID NCT06520397

First seen Mar 24, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This study is for adults with Crohn's disease who did not get enough help from the standard dose of a drug called ustekinumab. It compares two approaches: adding another drug (upadacitinib) to ustekinumab, versus increasing the dose of ustekinumab alone. The goal is to see which strategy better reduces gut inflammation and improves symptoms, while checking for side effects. About 214 participants will be randomly assigned to one of the two treatment groups.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wei Wang

    RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.