New depression drug DT-101 enters Mid-Stage trial

NCT ID NCT07610473

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase 2 trial tests whether DT-101 can ease depression symptoms in adults with major depressive disorder who are already on antidepressant medication. About 118 participants will receive either DT-101 or a placebo, and researchers will track changes in depression scores over 56 days. The goal is to see if DT-101 offers additional benefit beyond standard treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DT-101

What this could lead to

If it works, this could provide a new treatment option for people with major depressive disorder who are already on medication.

What could go wrong

This is an early-phase trial with only 118 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Draig Clinical Site

    RECRUITING

    DeSoto, Texas, 75115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Draig Clinical Site

    RECRUITING

    Miami, Texas, 33166, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••