Experimental combo for tough blood cancers tested, but trial stopped early

NCT ID NCT04937166

First seen Nov 11, 2025 · Last updated May 23, 2026 · Updated 28 times

Summary

This early-phase study tested a new drug called DSP107 combined with standard chemotherapy drugs (azacitidine with or without venetoclax) in adults with acute myeloid leukemia, myelodysplastic syndrome, or chronic myelomonocytic leukemia that had returned or not responded to up to two prior treatments. The goal was to check safety and find the best dose. The study was terminated early, so results are limited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MYELODYSPLASTIC SYNDROMES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • The University of Texas MD Anderson Cancer Center, Department of Leukemia

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.