Experimental combo for tough blood cancers shows early promise but trial halted

NCT ID NCT04937166

First seen Nov 11, 2025 · Last updated Jun 16, 2026 · Updated 32 times

Summary

This early-phase study tested a new drug called DSP107 combined with standard treatments for people with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or chronic myelomonocytic leukemia (CMML) that had come back or not responded to prior therapy. The goal was to find safe doses and check for signs of effectiveness. The trial was terminated early, so results are limited.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • The University of Texas MD Anderson Cancer Center, Department of Leukemia

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.