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Dry eye tests may reveal a new marker for hand osteoarthritis

NCT ID NCT07789054

Diagnosis Sponsor: Medipol University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time

Summary

Researchers are testing whether dry eye symptoms and signs can serve as a predictive marker in people with hand osteoarthritis. Participants complete the Ocular Surface Disease Index questionnaire and undergo tear tests, including Schirmer tests, tear break-up time, and optical coherence tomography. The study aims to see if these measures relate to each other and could help identify dry eye severity in this group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dry eye and ocular surface assessments, including Schirmer tests, tear break-up time, and optical coherence tomography
What this could lead to
If it works, this could point toward a simple way to spot dry eye severity in people with hand osteoarthritis, possibly aiding earlier care.
What could go wrong
This is a small, early study with only 23 participants, so the findings may not apply broadly. The tests measure symptoms and signs, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

23 people

The number who actually took part.

Started

Nov 2020

Finished

Apr 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of volunteered patients from our institution who presented with dry eye complaints and had a prior diagnosis of hand osteoarthritis according to the American College of Rheumatology (ACR) criteria. Patients with concurrent inflammatory rheumatic or autoimmune diseases, detected via blood tests, were excluded from the population to isolate the parameters. The final analyzed cohort comprises 23 patients who met all inclusion criteria and completed the comprehensive ocular surface and dry eye assessments

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with dry eye complaints. * Patients previously diagnosed with hand osteoarthritis according to the American College of Rheumatology (ACR) criteria. Exclusion Criteria: * Presence of inflammatory rheumatic or autoimmune inflammatory diseases detected by blood tests

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Conditions

The condition(s) this trial relates to.

dry eye syndrome osteoarthritis susceptibility 2

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dry eye syndrome (DES) Hand osteoarthritis

Contacts and locations

Locations

  • Istanbul Medipol University Pendik Hospital

    Istanbul, Turkey (Türkiye)

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