Cystic fibrosis drug combo put to the test with statins
NCT ID NCT07349394
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 1 study tested how a cystic fibrosis drug combo (vanzacaftor/tezacaftor/deutivacaftor) affects the body's processing of the statin rosuvastatin. 18 healthy adults took both medications to check for interactions and safety. The goal was to see if the drug combo changes rosuvastatin levels in the blood, which could guide future dosing for people with cystic fibrosis who also need statins.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vanzacaftor/Tezacaftor/Deutivacaftor (a triple combination drug for cystic fibrosis)
What this could lead to
If successful, this study could help doctors understand how to safely combine this cystic fibrosis treatment with common statins like rosuvastatin.
What could go wrong
This is a very early, small study in healthy people, not patients. It only checks drug interactions, not whether the treatment works for cystic fibrosis.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Altasciences - Kansas City
Overland Park, Kansas, 66212, United States