New drug interaction study for opioid treatments launches

NCT ID NCT07314346

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-stage study looks at how a new antiviral drug combination (BEM/RZR) affects the levels of two common opioid addiction treatments—buprenorphine/naloxone and methadone—in healthy adults. Researchers will give participants their usual opioid therapy plus the antiviral drug and measure drug concentrations in the blood. The goal is to see if the antiviral changes how these opioids work in the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bemnifosbuvir/Ruzasvir (BEM/RZR) combined with buprenorphine/naloxone or methadone

What this could lead to

If successful, this study could help doctors understand how to safely combine a new antiviral drug with common opioid addiction treatments.

What could go wrong

This is a very early, small study in healthy volunteers, not patients. It only checks drug levels, not whether the combination is safe or effective for treating disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atea Study Site

    RECRUITING

    Hollywood, Florida, 33019, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Atea Study Site

    RECRUITING

    Overland Park, Kansas, 66212, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Atea Study Site

    RECRUITING

    Marlton, New Jersey, 08053, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••