HEALTHY VOLUNTEER STUDY

This study tests a new drug that blocks a specific nerve channel (NaV1.8) to see which types of pain it reduces. Healthy volunteers receive tiny, safe doses injected into the skin and undergo brief pain tests like heat, cold, and pressure. The goal is to understand pain better an…

This early-stage study looks at how a single dose of the experimental drug combination bemnifosbuvir and ruzasvir is processed by the body in people with severe kidney or liver impairment compared to healthy volunteers. The goal is to gather safety and drug-level information, not…

This early-phase study looks at how heat stress changes the body's chemistry, especially in the kidneys, in 28 healthy volunteers. Researchers want to see if taking vitamin B3 (niacinamide) can alter the kidney's response to heat. The goal is to better understand kidney stress an…

This study looks at whether a simple, non-invasive vibration treatment can help prevent muscle loss and weakness when a leg is immobilized. Researchers will test 42 healthy adults aged 18-45 who are active but will have one leg temporarily unloaded. The goal is to see if focal mu…

This study looks at how the brain responds when different spots on the ear are gently touched. Healthy volunteers wear a cap with infrared light sensors to measure brain activity during the stimulation. The goal is to understand if different ear points produce different brain sig…

This study looks at how a new drug combination (BEM/RZR) affects the levels of buprenorphine/naloxone or methadone in the body. It involves 32 healthy adults who are on stable treatment for opiate withdrawal. The goal is to understand if the new drug changes how these medications…