HEALTHY VOLUNTEER STUDY

This early-stage study tests a new experimental drug, PF-08103402, for the first time in people. It includes healthy adults and adults with mild-to-moderate asthma to check safety, how the drug moves through the body, and whether food affects its absorption. Participants take the…

This study tests whether a small vibrating device placed on the thigh can prevent muscle loss when a leg is immobilized. Forty-two healthy adults will have one leg in a cast for several days. Half will receive daily vibration sessions; the other half will not. Researchers will me…

This study will intentionally expose 72 healthy adults to the bacteria that cause whooping cough to see how the body fights it off without immediate antibiotics. Participants will be monitored closely for up to 6 weeks before receiving antibiotics to clear the infection. The goal…

This early-stage study is testing a single dose of the drug combination bemnifosbuvir/ruzasvir in 28 adults. Some participants have severe kidney or liver impairment, while others are healthy. The goal is to see how the body processes the drug and whether it is safe in these grou…

This early-stage study looks at how a new antiviral drug combination (BEM/RZR) affects the levels of two common opioid addiction treatments—buprenorphine/naloxone and methadone—in healthy adults. Researchers will give participants their usual opioid therapy plus the antiviral dru…

This study looks at how gentle touch on different parts of the ear affects brain activity in 80 healthy adults. Participants wear a cap with infrared sensors to measure brain signals while a plastic filament gently stimulates points on both ears. The goal is to see if different e…

This early-phase study looks at how heat stress changes kidney function in 28 healthy, fit volunteers. Researchers want to understand the body's chemical responses and whether taking vitamin B3 (niacinamide) can influence those changes. The goal is to gather knowledge, not to tre…