Cure My Disease

Don't miss your cure!

 Log in / Sign up

Triple therapy may stop Kids' Post-Surgery vomiting

NCT ID NCT01739985

Symptom relief Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding a drug called droperidol to two standard anti-nausea medicines (ondansetron and dexamethasone) could better prevent vomiting after surgery in children at high risk. A total of 322 children aged 3 to 18 years took part. The main goal was to see if the three-drug combination reduced vomiting more effectively than the usual two-drug approach.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

322 people

The number who actually took part.

Start date

Dec 2010

Finished

May 2014

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

3 to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children scheduled for surgery and with high risk of postoperative vomiting, i.e. with VPOP score up to 4 * Between 3 to 18 years * Informed consent signed or the owner (s) of parental * Children receiving a social security system Exclusion Criteria: * Ambulatory surgery * Preoperative corticosteroids * Postoperative sedation * Allergy known to droperidol, ondansetron or dexamethasone * Known hypokaliemia * Known hypomagnesemia * Bradycardia (\<55 bpm) * Congenital long QT syndrome * Treatment that induce prolonged QT * Pheochromocytoma * Severe depressive syndrome

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Postoperative vomiting are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Postoperative Nausea and Vomiting Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative vomiting

Contacts and locations

Locations

  • Necker Hospital

    Paris, 75015, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.