New cocktail of 4 drugs shows promise for Hard-to-Treat myeloma

NCT ID NCT07150104

First seen Sep 30, 2025 · Last updated May 13, 2026 · Updated 31 times

Summary

This study tests a combination of four drugs (belantamab mafodotin, nirogacestat, pomalidomide, and dexamethasone) in people with multiple myeloma that has come back or not responded to at least three prior treatments. The goal is to find the safest dose and see how well the combination shrinks tumors. The trial is for adults aged 18 and older and is currently not recruiting new participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • GSK Investigational Site

    Salvador, Estado de Bahia, 41253-190, Brazil

  • GSK Investigational Site

    Porto Alegre, Rio Grande do Sul, 90110-270, Brazil

  • GSK Investigational Site

    Halifax, Nova Scotia, B3H 1V7, Canada

  • GSK Investigational Site

    Villejuif, 94805, France

  • GSK Investigational Site

    Mexico City, 01330, Mexico

  • GSK Investigational Site

    Oslo, 0450, Norway

  • GSK Investigational Site

    Lublin, 20-081, Poland

  • GSK Investigational Site

    Seoul, 03080, South Korea

  • GSK Investigational Site

    Ulsan, 44033, South Korea

  • GSK Investigational Site

    Falun, SE-791 82, Sweden

Conditions

Explore the condition pages connected to this study.