Massive down syndrome study aims to unlock health secrets
NCT ID NCT07625579
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This long-term study will follow up to 1,400 people with Down syndrome of all ages to better understand their health, development, and daily experiences. Participants and their caregivers will answer questions, share medical records, and may provide blood or saliva samples. Some may also take part in optional activities like sleep studies or brain imaging. The goal is to learn why certain health conditions are more common in Down syndrome and how to improve care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal why certain health conditions are more common in Down syndrome and point to ways to improve care and quality of life.
- What could go wrong
- This is an observational study, not a treatment trial. It may take years to produce actionable results, and findings may not apply to everyone with Down syndrome.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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John Hopkins University
NOT_YET_RECRUITINGBaltimore, Maryland, 21287, United States
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Kansas University Medical Center
NOT_YET_RECRUITINGKansas City, Kansas, 66160, United States
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St. Jude Children's Research Hospital
NOT_YET_RECRUITINGMemphis, Tennessee, 38105, United States
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Texas Children's Hosptial/Baylor College of Medicine
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
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The Children's Hospital of Philadelphia
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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The Children's Hospital of Philadelphia
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of California Irvine
NOT_YET_RECRUITINGOrange, California, 92868, United States
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University of Colorado Anschutz Medical Campus
NOT_YET_RECRUITINGAurora, Colorado, 80045, United States
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University of Miami
NOT_YET_RECRUITINGMiami, Florida, 33136, United States
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University of Minnesota
NOT_YET_RECRUITINGMinneapolis, Minnesota, 55455, United States
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University of North Carolina at Chapel Hill
NOT_YET_RECRUITINGChapel Hill, North Carolina, 27599, United States
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University of Pittsburgh
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15203, United States
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University of Texas Health Science Center at San Antionio
NOT_YET_RECRUITINGSan Antonio, Texas, 78207, United States
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University of Washington
NOT_YET_RECRUITINGSeattle, Washington, 98195, United States
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University of Wisconsin-Madison
RECRUITINGMadison, Wisconsin, 53705, United States
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Washington University in St. Louis
NOT_YET_RECRUITINGSt Louis, Missouri, 63108, United States
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Other studies related to the condition(s) this trial covers.
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