Massive down syndrome study aims to unlock health secrets

NCT ID NCT07625579

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This long-term study will follow up to 1,400 people with Down syndrome of all ages to better understand their health, development, and daily experiences. Participants and their caregivers will answer questions, share medical records, and may provide blood or saliva samples. Some may also take part in optional activities like sleep studies or brain imaging. The goal is to learn why certain health conditions are more common in Down syndrome and how to improve care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal why certain health conditions are more common in Down syndrome and point to ways to improve care and quality of life.

What could go wrong

This is an observational study, not a treatment trial. It may take years to produce actionable results, and findings may not apply to everyone with Down syndrome.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chromosomal disorder developmental disability Down syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • John Hopkins University

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kansas University Medical Center

    NOT_YET_RECRUITING

    Kansas City, Kansas, 66160, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Jude Children's Research Hospital

    NOT_YET_RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hosptial/Baylor College of Medicine

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Children's Hospital of Philadelphia

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • The Children's Hospital of Philadelphia

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California Irvine

    NOT_YET_RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-••••

  • University of Colorado Anschutz Medical Campus

    NOT_YET_RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-••••

  • University of Miami

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Minnesota

    NOT_YET_RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of North Carolina at Chapel Hill

    NOT_YET_RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Health Science Center at San Antionio

    NOT_YET_RECRUITING

    San Antonio, Texas, 78207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Washington

    NOT_YET_RECRUITING

    Seattle, Washington, 98195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Wisconsin-Madison

    RECRUITING

    Madison, Wisconsin, 53705, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University in St. Louis

    NOT_YET_RECRUITING

    St Louis, Missouri, 63108, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••