New pill shows promise for tough lung cancer

NCT ID NCT07231068

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new oral drug called dositinib in people with advanced non-small cell lung cancer that has a specific EGFR mutation. The trial has two parts: first, finding the safest dose, then testing that dose in a larger group. Researchers will monitor side effects, how the drug moves through the body, and whether it shrinks tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dositinib mesylate tablets (90-1408)

What this could lead to

If successful, this could provide a new targeted treatment option for people with advanced EGFR-mutant lung cancer.

What could go wrong

This is an early-phase trial with small numbers, so safety and effectiveness are not yet proven. Side effects are possible, and the drug may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, China

  • Henan Provincial Cancer Hospital

    RECRUITING

    Zhengzhou, China

  • Henan Provincial People's Hospital

    RECRUITING

    Zhengzhou, China

  • Peking Union Medical College Hospital

    WITHDRAWN

    Beijing, China

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    RECRUITING

    Guangzhou, China