Ultrasound-Guided stenting may cut heart risks in complex cases
NCT ID NCT03770650
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using intravascular ultrasound (IVUS) to guide a specific stenting technique (DK crush) leads to fewer heart problems than standard angiography guidance. About 556 adults with complex coronary bifurcation lesions will be randomly assigned to one of the two approaches. The main goal is to see if IVUS reduces the combined risk of cardiac death, heart attack, or need for repeat artery-opening procedures within 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
drug-eluting stent (SYNERGY)
What this could lead to
If successful, this could show that using IVUS guidance during stenting reduces the risk of heart attack, repeat procedures, or cardiac death in people with complex coronary blockages.
What could go wrong
This is a mid-stage trial with 556 participants, so results may not apply to all patients. The benefit of IVUS over standard angiography may be small, and there are always risks like stent clotting or vessel injury.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Nanjing First Hospital
Nanjing, Jiangsu, 210006, China