Schizophrenia protein may flag hidden heart risk

NCT ID NCT06304233

Ongoing Knowledge-focused Sponsor: Norwegian University of Science and Technology Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study investigates whether a protein called DISC1, known for its role in schizophrenia, is also linked to heart function in people with the condition. Researchers will measure DISC1 levels in blood and use heart imaging (echocardiograms, cardiac MRI, and ECGs) to assess heart structure and performance in 120 adults with schizophrenia. The goal is to see if DISC1 could serve as a biomarker for heart disease, which is more common in this population.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If a link is found, it could point toward a new way to identify heart disease risk in people with schizophrenia, potentially leading to earlier monitoring or treatment.
What could go wrong: This is an observational study, not a treatment trial. It may find no clear connection, and results may not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART DISEASES HEART; FUNCTIONAL DISTURBANCE SCHIZOPHRENIA

Contacts and locations

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Locations

Norwegian University of Science and Technology

Trondheim, Norway
St Olavs Hospital, Trondheim University Hospital

Trondheim, Norway

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