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Withdrawn study sought to unlock back pain mystery

NCT ID NCT04134910

Terminated Knowledge-focused Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aimed to understand how physical therapy affects spinal discs in people with low back pain. Researchers planned to use MRI scans to measure changes in the discs before and after 6 weeks of therapy. The goal was to see if these scans could predict which patients would feel better. However, the study was withdrawn before any participants were enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Physical therapy
What this could lead to
If successful, this could help identify which back pain patients are most likely to benefit from physical therapy.
What could go wrong
The study was withdrawn before enrolling anyone, so no results are available. It was also small and exploratory, so even if completed, findings might not apply broadly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Back Pain intervertebral disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACK PAIN INTERVERTEBRAL DISC DEGENERATION

Contacts and locations

Locations

  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

    Philadelphia, Pennsylvania, 19104-4551, United States

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