New sickle cell drug enters human testing – could ease painful crises?

NCT ID NCT07187973

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 25 times

Summary

This early-stage study tests a new drug, DISC-3405, in 24 adults with sickle cell disease. The main goal is to check safety and how the body handles the drug at different doses. Researchers will also measure changes in blood counts to see if the drug might help control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Augusta University

    RECRUITING

    Augusta, Georgia, 30912, United States

    Contact

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Innovative Hematology - Indiana Hemophilia & Thrombosis Center

    RECRUITING

    Indianapolis, Indiana, 46260, United States

    Contact

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mount Sinai Hospital

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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