New supplement trial aims to boost weight loss and energy in overweight adults

NCT ID NCT07322679

Not yet recruiting Symptom relief Sponsor: Nanjing Nutrabuilding Bio-tech Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking dihydroberberine (DHB) daily for 12 weeks can improve body weight, blood sugar control, energy, appetite, and mood in healthy adults aged 35-55 who are overweight or mildly obese. Participants will be randomly assigned to receive DHB or a placebo, and will undergo tests including body scans and meal challenges. The goal is to see if DHB offers any benefits beyond a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dihydroberberine (DHB)
What this could lead to: If it works, this could point toward a natural supplement for managing weight and improving energy and mood in people with mild obesity.
What could go wrong: This is an early-stage trial with only 120 participants, so results may not apply to everyone. The supplement may show no benefit over placebo, and long-term safety is not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEALTH ADULT SUBJECTS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTH ADULT SUBJECTS

Contacts and locations

Locations

Biofortis, Merieux NutriSciences

Addison, Illinois, 60101, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.