New supplement trial aims to boost weight loss and energy in overweight adults
NCT ID NCT07322679
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking dihydroberberine (DHB) daily for 12 weeks can improve body weight, blood sugar control, energy, appetite, and mood in healthy adults aged 35-55 who are overweight or mildly obese. Participants will be randomly assigned to receive DHB or a placebo, and will undergo tests including body scans and meal challenges. The goal is to see if DHB offers any benefits beyond a placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dihydroberberine (DHB)
What this could lead to
If it works, this could point toward a natural supplement for managing weight and improving energy and mood in people with mild obesity.
What could go wrong
This is an early-stage trial with only 120 participants, so results may not apply to everyone. The supplement may show no benefit over placebo, and long-term safety is not yet known.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Biofortis, Merieux NutriSciences
Addison, Illinois, 60101, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••