Diet showdown: keto vs. mediterranean for fibromyalgia relief

NCT ID NCT07517757

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether different diets—a very low-calorie ketogenic diet, a Mediterranean diet, or a Mediterranean diet with added probiotics—can reduce pain and improve quality of life in women with fibromyalgia who are overweight or mildly obese. Researchers will track pain, sleep, mood, and gut health over 12 weeks. The goal is to find a practical, non-drug approach to managing fibromyalgia symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dietary interventions (very low-calorie ketogenic diet, Mediterranean diet, and Mediterranean diet with probiotics)
What this could lead to
If successful, this could point toward a simple, drug-free way to reduce pain and improve sleep, mood, and daily function in women with fibromyalgia.
What could go wrong
This is a small, early-stage study with only 90 participants, so results may not apply to everyone. Dietary changes can be hard to stick with, and the effects may vary from person to person.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Internal and Medical Specialities (university of Genoa)

    Genova, Genova, 16132, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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