Dietary strategy may keep weight off after stopping semaglutide

NCT ID NCT07711548

Not yet recruiting Disease control Sponsor: Knut Mai Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 21, 2026 · Updated 2 times

Summary

This trial tests whether two specific diet plans can help people with obesity or overweight maintain weight loss after stopping semaglutide (Wegovy). Many patients regain weight quickly when they stop the drug. The study compares a special dietary pattern called NutriAct plus with a rescue very low calorie diet for those who regain weight. Participants must have a BMI of 27 or higher with risk factors, or 30 or higher, and cannot have type 2 diabetes or certain other conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dietary patterns (NutriAct plus and rescue very low calorie diet)
What this could lead to
If successful, this could provide a practical diet strategy to prevent weight regain after stopping semaglutide, making intermittent treatment more feasible.
What could go wrong
This is a behavioral intervention study, not a drug trial, so results depend heavily on adherence. The diets may not be sustainable for everyone, and weight regain could still occur.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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