Could a painkiller help treat alcoholism? scientists investigate

NCT ID NCT06029296

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether a single dose of diclofenac, a common pain reliever, can change a specific brain chemical in people with alcohol use disorder. Twelve adults with mild to severe alcohol use disorder will receive either diclofenac or a placebo in a double-blind fashion. The goal is to see if diclofenac increases kynurenic acid levels, which may help understand how the brain works in addiction. This is an early-stage study focused on learning, not treatment.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Maryland Psychiatric Research Center (MPRC) Treatment Research Program (TRP)

    Catonsville, Maryland, 21228, United States