Could a new drug replace opioids for cooling babies?

NCT ID NCT04772222

Completed Symptom relief Sponsor: University of Utah Source: ClinicalTrials.gov ↗

First seen Mar 20, 2026 · Last updated Apr 30, 2026 · Updated 4 times

Summary

This study tested a drug called dexmedetomidine (DMT) against morphine for sedation and pain relief in 50 newborn babies with brain injury who were undergoing cooling therapy. The goal was to see if DMT is safer and works as well as morphine, which can have long-term side effects. Researchers also measured drug levels in the blood to find the best dose for future larger studies.

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Contacts and locations

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Locations

Intermountain Medical Center

Murray, Utah, 84107, United States
McKay-Dee Hospital

Ogden, Utah, 84403, United States
Primary Children's Hospital

Salt Lake City, Utah, 84113, United States
University of Utah Health

Salt Lake City, Utah, 84132, United States
Utah Valley Hospital

Provo, Utah, 84604, United States

Conditions

Explore the condition pages connected to this study.

HYPOXIC ISCHEMIC ENCEPHALOPATHY PAIN