Could a daily pill replace chemo for some breast cancer patients?

NCT ID NCT07615751

First seen Jun 04, 2026 · Last updated Jun 12, 2026 · Updated 2 times

Summary

This phase 3 study compares an all-oral, chemotherapy-free drug combination (pyrotinib, trastuzumab subcutaneous, and dalpiciclib) against a standard chemo-containing regimen for advanced HER2-positive breast cancer. About 502 adults who have had at most one prior treatment for advanced disease will participate. The goal is to see if the pill-only option works as well as chemo while being less toxic and more convenient.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan Cancer Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200230, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.