Does diabetes leave its mark on Women's hair? scalp scans put the question under the microscope
NCT ID NCT07817277
First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time
Summary
Researchers at Al-Azhar University are studying whether type 2 diabetes is linked to changes in women's hair and scalp. The study compares 130 women aged 20 to 60, half with diabetes for at least a year and half healthy controls matched by age. Participants undergo clinical hair exams, dermoscopic scalp imaging, blood tests for HbA1c, ferritin, vitamin D, and thyroid function, plus questionnaires about hair loss severity. The goal is to describe any differences in hair density, shaft thickness, and scalp patterns between the two groups.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a clear link emerges, doctors could one day screen diabetic women for hair and scalp changes as an early warning sign of poor blood sugar control.
- What could go wrong
- This is an observational study, so it can only show associations, not cause and effect. Any link found may reflect other factors such as age, ferritin, vitamin D, or thyroid status rather than diabetes itself.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 130 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The patients will be recruited from the dermatology and endocrinology outpatient clinics of Al-Zahraa University Hospital. The patients will be recruited from the dermatology and endocrinology outpatient clinics of Al-Zahraa University Hospital. Inclusion criteria • Cases: o Female patients aged 20-60 years o Diagnosed with type 2 diabetes mellitus for at least 1 year o HbA1c ≥ 6.5% o Consent to participate • Controls: o Age-matched healthy females (no history of diabetes or insulin resistance) o Normal fasting blood sugar (\<100 mg/dL) and HbA1c (\<5.7%) o No known chronic illness o Consent to participate Exclusion Criteria (for both groups) • Current pregnancy or lactation • Thyroid dysfunction • Polycystic ovary syndrome (PCOS) • Anemia (Hb \< 10 g/dL) • History of chemotherapy, radiotherapy, or recent acute illness • Scalp diseases (e.g., tinea capitis, scarring alopecia) • Recent use of drugs known to affect hair growth (e.g., isotretinoin, spironolactone).
- Ages
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20 to 60 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Cases: * Female patients aged 20-60 years * Diagnosed with type 2 diabetes mellitus for at least 1 year * HbA1c ≥ 6.5% o Consent to participate * Controls: * Age-matched healthy females (no history of diabetes or insulin resistance) * Normal fasting blood sugar (\<100 mg/dL) and HbA1c (\<5.7%) o No known chronic illness * Consent to participate Exclusion Criteria: * Current pregnancy or lactation * Thyroid dysfunction • Polycystic ovary syndrome (PCOS) * Anemia (Hb \< 10 g/dL) * History of chemotherapy, radiotherapy, or recent acute illness * Scalp diseases (e.g., tinea capitis, scarring alopecia) * Recent use of drugs known to affect hair growth (e.g., isotretinoin, spironolactone)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Al Zahraa hospital
Cairo, Cairo Governorate, Egypt
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