Gene therapy may free kids from daily cystinosis meds

NCT ID NCT06910813

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a gene therapy called DFT383 in 30 children aged 2 to 5 with nephropathic cystinosis, a rare disease that damages kidneys and other organs. The treatment aims to fix the genetic problem so children may no longer need daily cysteamine medication. Researchers will check safety and whether the therapy can reverse kidney problems.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cystinosis Fanconi renotubular syndrome lysosomal storage disease nephropathic cystinosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Baylor College of Medicine - Texas Children's Hospital (recuiting Cohort 0)

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Emory University School of Medicine - Children's Healthcare of Atlanta (recuiting Cohort 0)

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stanford University - Stanford Children's Health

    RECRUITING

    Stanford, California, 94305, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California at San Diego - Rady Children's Hospital

    RECRUITING

    San Diego, California, 92123, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact