Which anesthetic protects the injured brain better?

NCT ID NCT07244822

Completed Symptom relief Sponsor: Universitas Jenderal Soedirman Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study tested two different anesthetic drugs—dexmedetomidine and sufentanil—in 28 people having surgery for traumatic brain injury. The goal was to see which one keeps the brain's oxygen levels more stable during and after the operation. Researchers measured oxygen saturation in the brain using a special light-based monitor. The results could help doctors choose the best anesthetic for these critical surgeries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexmedetomidine and Sufentanil
What this could lead to: If dexmedetomidine proves better at maintaining brain oxygen levels, it could become a preferred anesthetic for traumatic brain injury surgery.
What could go wrong: This is a very small, completed trial (28 people) that only measures a short-term oxygen level, not long-term recovery or survival. Results may not apply to all TBI patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CEREBRAL OXYGEN SATURATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL OXYGEN SATURATION NIR SPECTROSCOPY TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

RSUD Prof. Margono Soekarjo

Purwokerto, Central Java, 53122, Indonesia

More trials for these conditions

Other studies related to the condition(s) this trial covers.