Which drug keeps you safer on the operating table? new study pits dexmedetomidine against fentanyl

NCT ID NCT07238101

Completed Symptom relief Sponsor: Universitas Sumatera Utara Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested two drugs, dexmedetomidine and fentanyl, to see which one keeps heart rate and blood pressure more stable during spine surgery. Fifty adults having elective spine surgery received one of the two drugs as part of their anesthesia. Researchers measured their blood pressure and heart rate at several points during the operation to compare how well each drug maintained stability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexmedetomidine and fentanyl
What this could lead to: If one drug proves better, it could help anesthesiologists choose the safer option for spine surgery patients.
What could go wrong: This is a small, completed Phase 4 trial with only 50 participants, so results may not apply to everyone. Both drugs have known side effects like low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMODYNAMIC STABILITY DURING ANESTHESIA SPINE SURGERY

Contacts and locations

Locations

Faculty of Medicine, Universitas Sumatera Utara

Medan, North Sumatra, 20222, Indonesia

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