Can a pre-surgery spray fix post-op sleep? new trial investigates

NCT ID NCT07622355

Ongoing Symptom relief Sponsor: The Second People's Hospital of Huai'an Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving dexmedetomidine—either as a nasal spray or through an IV—before thyroid surgery can improve sleep quality afterward. 120 adults undergoing thyroid removal will be randomly assigned to one of two drug groups or a placebo. The goal is to see if this approach reduces sleep problems, pain, and side effects, helping patients recover better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexmedetomidine
What this could lead to: If it works, this could point toward a simple way to improve sleep and recovery after thyroid surgery.
What could go wrong: This is an early-phase trial with only 120 participants, so results may not apply to everyone. The drug may not improve sleep significantly compared to placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign thyroid gland neoplasm thyroid cancer thyroid gland disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

THYROID DISEASES

Contacts and locations

Locations

The Affiliated Huaian Hospital of Xuzhou Medical University, Huai'an Second Hospital, Huaian

Huai'an, China

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