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Drug-Releasing implant aims to boost hearing for adults with severe loss

NCT ID NCT06424262

Completed Symptom relief Sponsor: Cochlear Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests a new cochlear implant that slowly releases dexamethasone, a drug that reduces inflammation after surgery. The goal is to see if it works better than a standard implant for adults with severe hearing loss. About 48 adults will be randomly assigned to get either the new or standard implant and will be followed for 12 months.

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Conditions

The condition(s) this trial relates to.

cochlear disorder hearing loss disorder Hearing Loss, Bilateral Hearing Loss, Sensorineural sensorineural hearing loss disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEARING LOSS, BILATERAL HEARING LOSS, BILATERAL SENSORINEURAL HEARING LOSS, COCHLEAR HEARING LOSS, SENSORINEURAL

Contacts and locations

Locations

  • Centre Hospitalier Universitaire Toulouse

    Toulouse, France

  • Centre Hospitalier Universitaire de Lille

    Lille, France

  • Hôpital Universitaire Pitié-Salpêtrière

    Paris, France

  • Macquarie University

    Sydney, New South Wales, Australia

  • Manchester Royal Infirmary

    Manchester, United Kingdom

  • Medizinische Hochschule Hannover

    Hanover, Lower Saxony, Germany

  • Royal Prince Alfred Hospital

    Sydney, New South Wales, Australia

  • Royal Victorian Eye and Ear Hospital

    Melbourne E., Victoria, Australia

  • St Vincent Private Hospital

    Melbourne, Victoria, Australia

  • Universitätsklinikum Freiburg

    Freiburg im Breisgau, Freiburg Im Breisgau, Germany

  • Westmead Private Hospital

    Sydney, New South Wales, Australia

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