Could a common steroid tame deadly dengue?
NCT ID NCT05631405
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether the steroid dexamethasone can help people with severe dengue. The researchers will give either dexamethasone or a placebo to 200 infected adults in Thailand. They want to see if the drug lowers the death rate and shortens hospital stays.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dexamethasone
- What this could lead to
- If it works, this could point toward a simple, cheap treatment to reduce deaths and shorten hospital stays for severe dengue patients.
- What could go wrong
- This is a relatively small, early-stage trial. Steroids can have side effects, and previous studies on steroids for dengue have had mixed results, so there is no guarantee of benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chulalongkorn University
RECRUITINGBangkok, Thailand
-
King Chulalongkorn Memorial Hospital
RECRUITINGBangkok, Thailand
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