Could a common steroid tame deadly dengue?

NCT ID NCT05631405

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether the steroid dexamethasone can help people with severe dengue. The researchers will give either dexamethasone or a placebo to 200 infected adults in Thailand. They want to see if the drug lowers the death rate and shortens hospital stays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dexamethasone

What this could lead to

If it works, this could point toward a simple, cheap treatment to reduce deaths and shorten hospital stays for severe dengue patients.

What could go wrong

This is a relatively small, early-stage trial. Steroids can have side effects, and previous studies on steroids for dengue have had mixed results, so there is no guarantee of benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dengue disease Dengue hemorrhagic fever dengue shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chulalongkorn University

    RECRUITING

    Bangkok, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • King Chulalongkorn Memorial Hospital

    RECRUITING

    Bangkok, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••