Can a common steroid ease cancer symptoms? new trial investigates
NCT ID NCT00489307
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether dexamethasone, a steroid, can help control fatigue, pain, nausea, and other symptoms in 132 adults with advanced solid tumors. Participants take the drug or a placebo by mouth twice daily for 14 days. The main goal is to see if symptoms improve, measured by a fatigue questionnaire.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexamethasone (a steroid drug)
What this could lead to
If it works, this could provide a short-term option to reduce common symptoms like fatigue and pain in people with advanced cancer.
What could go wrong
This is a small, early-phase trial with only 132 participants. Results may not apply to all cancer types, and dexamethasone can have side effects like increased appetite or mood changes.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Lyndon Baines Johnson Hospital
Houston, Texas, 77030, United States
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States