Rethinking Pre-Med: could skipping allergy drugs improve IBD treatment?

NCT ID NCT07385131

First seen Feb 03, 2026 · Last updated Apr 28, 2026 · Updated 10 times

Summary

This study looks at whether people with moderate-to-severe inflammatory bowel disease (IBD) need to take dexamethasone (a steroid) before their infliximab infusion to prevent allergic reactions. Researchers will compare patients who get the routine pre-medication with those who don't, to see if skipping it is safe and reduces side effects. The goal is to personalize care and avoid unnecessary medications. About 300 participants aged 14-80 with Crohn's disease or ulcerative colitis will be observed over their first four treatments.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Second Affiliated Hospital, School of Medicine, Zhejiang University

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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