New hope for PSC: can a Vitamin-Based drug calm the liver?

NCT ID NCT05835505

First seen Nov 06, 2025 · Last updated May 19, 2026 · Updated 26 times

Summary

This study tests whether the drug BRS201 (a form of vitamin B12) can lower liver enzyme levels in people with primary sclerosing cholangitis (PSC), a chronic liver disease. About 28 adults with PSC will take the drug or a placebo for 4 weeks each, in random order, and have their blood and stool tested. All visits are done remotely for convenience.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Chestnut Hill, Massachusetts, 02467, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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