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5-Day brain zaps could lift depression in seniors

NCT ID NCT07212465

Recruiting now Symptom relief Sponsor: Rotman Research Institute at Baycrest Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a 5-day course of deep transcranial magnetic stimulation (dTMS) can safely reduce depression in adults aged 60-85 who haven't improved with medication. Participants receive either real or placebo stimulation to the brain's anterior cingulate cortex. The goal is to see if this accelerated protocol is tolerable and effective for easing depressive symptoms.

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Conditions

The condition(s) this trial relates to.

Depressive Disorder, Treatment-Resistant major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER (MDD)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rotman Research Institute at Baycrest

    RECRUITING

    Toronto, Ontario, M6A 2E1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••