Perimenopause depression study halted after just 2 volunteers

NCT ID NCT05329779

First seen Jan 23, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This study aimed to understand how a natural brain chemical called allopregnanolone influences depression in women going through perimenopause. Researchers planned to measure changes in mood and thinking patterns. However, the study was stopped early and only enrolled 2 participants, so no meaningful conclusions were reached.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.