New hope for tough depression: Add-On drug shows promise

NCT ID NCT05593029

Summary

This study tested whether adding an experimental drug called SEP-363856 to standard antidepressants helps adults whose depression hasn't improved enough with previous treatments. About 929 adults with major depressive disorder participated in this late-stage trial. Researchers compared the drug against a placebo to see if it reduced depression symptoms more effectively.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • A-Shine s.r.o.

    Ptzen, Plzeň Region, 30100, Czechia

  • AMR Convention Research

    Warrenville, Illinois, 60555, United States

  • ATP Clinical Research, Inc.

    Orange, California, 92868, United States

  • Adams Clinical

    Watertown, Massachusetts, 02471, United States

  • Advanced Discovery Research LLC

    Atlanta, Georgia, 30318, United States

  • Alliance Research

    Long Beach, California, 90807, United States

  • Ambulatory for Group Practice for Specialized Psychiatrics Help PHILIPOPOLIS OOD

    Plovdiv, 4002, Bulgaria

  • Anderson Clinical Research

    Redlands, California, 92374, United States

  • Arztepartnerschaft Dr. med. J. Springhub/ W. Schwarz-Studienzentrum Nord-West

    Westerstede, 26655, Germany

  • BRAIN-SOULTHERAPY s.r.o.

    Kladno, Central Bohemia, 272 01, Czechia

  • Basil Clinical

    Inwood, New York, 11096, United States

  • Benchmark Research

    Shreveport, Louisiana, 71101, United States

  • Berman Clinical

    New York, New York, 10029, United States

  • Boston Clinical Trials

    Roslindale, Massachusetts, 02131, United States

  • California Mental Behavioral Health

    Santee, California, 92071, United States

  • Cenexel CBH (CBH Health)

    Gaithersburg, Maryland, 20877, United States

  • Center for Emotional Fitness

    Cherry Hill, New Jersey, 08002, United States

  • Central Miami Medical Institute

    Miami, Florida, 33125, United States

  • Centre for Addiction and Mental Health (CAMH & University of Toronto)

    Toronto, Ontario, M6J 1H4, Canada

  • Centrum Medyczne Luxmed Sp.z. o.o.

    Lublin, 20-109, Poland

  • Chatham-Kent Clinical Trials Research Centre

    Chatham, Ontario, N7L 1C1, Canada

  • ClinExpert Kft.

    Budapest, 1033, Hungary

  • Clinical Neuroscience Solutions Inc.

    Jacksonville, Florida, 32256, United States

  • Clinical Neuroscience Solutions Inc.

    Memphis, Tennessee, 38119, United States

  • Clinical Neuroscience Solutions Inc. dba CNS Healthcare

    Orlando, Florida, 32801, United States

  • Clintrial s.r.o.

    Prague, 10000, Czechia

  • Collaborative NeuroScience Research , LLC

    Garden Grove, California, 92845, United States

  • Collaborative Neuroscience Research LLC

    Torrance, California, 90504, United States

  • Combined Research Orlando Phase I-IV

    Orlando, Florida, 32807, United States

  • Community Clinical Research, Inc.

    Austin, Texas, 78754, United States

  • Copley Clinical

    Boston, Massachusetts, 02116, United States

  • Core Clinical Research

    Everett, Washington, 98201, United States

  • DCC-Mladost M OOD

    Varna, 9020, Bulgaria

  • DM Clinical Research - Belliare

    Houston, Texas, 77081, United States

  • DelSol Research

    Tucson, Arizona, 85715, United States

  • Diagnostic Consultive Center Higya AD

    Pazardzhik, 4400, Bulgaria

  • Donald J. Garcia, Jr., MD, PA

    Austin, Texas, 78737, United States

  • FutureSearch Trials of Dallas

    Dallas, Texas, 75251, United States

  • Indywidualna SpecjalistycznaPraktyka Lekarska AgnieszkaRemlinger-Molenda

    Szkolkarska 32, 62-002, Poland

  • Institute of Living Hartford Hospital

    Hartford, Connecticut, 06106, United States

  • Institute of Mental Health Research IMHR

    Ottawa, Ontario, K1Z 7K4, Canada

  • Integrative Clinical Trials

    Brooklyn, New York, 11229, United States

  • Interventional Psychiatry of Tampa Bay

    Tampa, Florida, 33629, United States

  • K2 Medical Research

    Maitland, Florida, 32751, United States

  • K2 Medical Research

    Tampa, Florida, 33607, United States

  • Manhattan Behavioral Medicine PLLC

    New York, New York, 10036, United States

  • Medical Center Sveti Naum

    Sofia, 1113, Bulgaria

  • Mental Health Center Vratsa

    Vratsa, 3000, Bulgaria

  • MetroMed Clinical Trials

    Chicago, Illinois, 60614, United States

  • MlynowaMed - Bialystok

    Bialystok, OH, 15-404, Poland

  • National Institute of Mental Health

    Klecany, 25067, Czechia

  • Neurobehavioral Medicine Group

    Bloomfield Hills, Michigan, 48302, United States

  • North Texas Clinical Trials

    Fort Worth, Texas, 76104, United States

  • Osrodek Badan Klinicznych CLINSANTE

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-794, Poland

  • Patient Priority Clinical Studies LLC

    Cincinnati, Ohio, 45215, United States

  • Pharmakologisches Studienzentrum Chemnitz GmbH

    Chemnitz, MA, 09111, Germany

  • Pillar Clinical Research

    Bentonville, Arkansas, 72712, United States

  • Praktyka Lekarska Malgorzata Wojtanowska-Bogacka

    Poznan, Greater Poland Voivodeship, 60-192, Poland

  • Precise Research Centers

    Flowood, Mississippi, 39232, United States

  • Private Practice Kusserow

    Stralsund, Mecklenburg-Vorpommern, 18439, Germany

  • ProScience Research Group

    Culver City, California, 90230, United States

  • Psychiatric And Behavioral Solutions, LLC

    Millcreek, Utah, 84124, United States

  • Renew Health Clinical Research

    Snellville, Georgia, 30078, United States

  • Schuster Medical Research Institute SMRI

    Sherman Oaks, California, 91403, United States

  • Scottsdale Clinical Research

    Scottsdale, Arizona, 85260, United States

  • Semmelweis University

    Budapest, M6J 1H4, Hungary

  • Somni Bene Institut for Medical Research

    Schwerin, Mecklenburg, 19053, Germany

  • Sooner Clinical Research

    Oklahoma City, Oklahoma, 73116, United States

  • Suburban Research Associates

    West Chester, Pennsylvania, 19380, United States

  • Sunwise Clinical Research with is in Lafayette, CA

    Walnut Creek, California, 94596, United States

  • The Medical Research Network, LLC

    New York, New York, 10128, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • Velocity Clinical Research Wiesbaden

    Wiesbaden, Hesse, 65189, Germany

  • Viking Clinical Research

    Temecula, California, 92591, United States

  • Vitalix Clinical

    Worcester, Massachusetts, 01608, United States

  • Wr-Pri, Llc

    Encino, California, 91316, United States

Conditions

Explore the condition pages connected to this study.