New depression pill faces off against leading drug in major trial
NCT ID NCT07253207
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new drug, levomilnacipran, for treating major depression. It involved 392 adults aged 18 to 65 with moderate to severe depression. The drug was compared to duloxetine, a commonly used antidepressant, over 8 weeks to see how well it eased symptoms and if it was safe.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Brain Hospital of Guangzhou Medical University
Guangzhou, Guangdong, 510370, China
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Beijing Anding Hospital Capital Medical University
Beijing, Beijing Municipality, 100000, China
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Beijing HuiLongGuan Hospital
Beijing, Beijing Municipality, 102200, China
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Chengdu Fourth People's Hospital
Chengdu, Sichuan, 610041, China
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Chongqing Mental Health Center
Chongqing, Chongqing Municipality, 401147, China
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Hangzhou Seventh People's Hospital
Hangzhou, Zhejiang, 310007, China
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Hebei Provincial Mental Health Center
Baoding, Hebei, 071030, China
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Hefei Fourth People's Hospital
Hefei, Anhui, 230031, China
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Hunan Provincial Second People's Hospital
Changsha, Hunan, 410007, China
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Huzhou Third People's Hospital
Huzhou, Zhejiang, 313000, China
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Jiangxi Provincial Psychiatric Hospital
Nanchang, Jiangxi, 330029, China
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Jilin Provincial Neuropsychiatric Hospital
Siping, Jilin, 136000, China
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Linfen Central Hospital
Linfen, Shanxi, 041099, China
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Nantong Mental Health Center
Nantong, Jiangsu, 226005, China
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Ningbo University Affiliated Kangning Hospital
Ningbo, Zhejiang, 315201, China
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Shandong Provincial Mental Health Center
Jinan, Shandong, 250014, China
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Shanghai Pudong New Area Mental Health Center
Shanghai, Shanghai Municipality, 200124, China
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Suzhou Guangji Hospital
Suzhou, Jiangsu, 215131, China
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The First Affiliated Hospital of Kunming Medical University
Kunming, Yunnan, 650032, China
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The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330006, China
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The First Affiliated Hospital of Xi 'an Jiaotong University
Xi'an, Shaanxi, 710061, China
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The First Hospital of Hebei Medical University
Shijiazhuang, Hebei, 050000, China
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The First Hospital of Shanxi Medical University
Taiyuan, Shanxi, 030001, China
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Tianjin Fourth Central Hospital
Tianjin, Tianjin Municipality, 300074, China
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Wuhu Hospital of Beijing Anding Hospital, Capital Medical University
Wuhu, Anhui, 241003, China
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Wuxi Mental Health Center
Wuxi, Jiangsu, 214000, China
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Xi 'an Mental Health Center
Xi'an, Shaanxi, 710199, China
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Zhenjiang Mental Health Center
Zhenjiang, Jiangsu, 212021, China
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Other studies related to the condition(s) this trial covers.
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