Could cheaper scans replace MRI for women with dense breasts?

NCT ID NCT06636370

Recruiting now Diagnosis Sponsor: C.H. van Gils Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

Women with extremely dense breasts have a higher risk of breast cancer, and tumors are harder to see on standard mammograms. This large study of 36,000 women aged 50-75 will test two extra screening methods—contrast-enhanced mammography and a shorter MRI—to see if they can find cancers earlier without overloading the healthcare system. Participants will get one of these scans after a normal mammogram, and researchers will track how many cancers are found between screenings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Contrast-enhanced mammography (CEM) and abbreviated MRI (AB-MRI)
What this could lead to: If successful, this could provide a more affordable and practical way to screen women with dense breasts for cancer, catching tumors earlier and reducing deaths.
What could go wrong: The trial is still recruiting and results are not yet available. The new methods may not be as effective as full MRI, or may cause more false alarms or side effects from contrast dye.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

UMC Utrecht
RECRUITING

Utrecht, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.