Brain zaps for depression? tiny study hopes to lift the fog
NCT ID NCT01798407
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small pilot study tests whether deep brain stimulation (DBS) aimed at a specific brain region called the lateral habenula can safely reduce symptoms in 6 adults with severe, treatment-resistant depression. Participants have either major depressive disorder or bipolar I and have not responded to standard treatments. The main goal is to see if depression scores drop by at least half after 6 months of stimulation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BIPOLAR DISORDER I are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Baylor College of Medicine
Houston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which works best for stubborn depression? adding a drug, brain stimulation, or switching meds?
- Fast brain stimulation shows promise for stubborn depression
- Ketamine booster for shock therapy? new trial aims to lift depression and protect memory
- Could an arthritis drug lift the fog of Treatment-Resistant depression?
- Can a gentler brain stimulation replace ECT for tough depression?
- Can ketamine plus therapy curb suicidal thoughts? new trial aims to find out.