Brain zaps for depression: tiny trial hopes to lift the darkest moods
NCT ID NCT01798407
First seen Dec 17, 2025 · Last updated May 21, 2026 · Updated 28 times
Summary
This small pilot study tests whether deep brain stimulation (DBS) targeting a specific brain region can safely reduce severe depression in 6 adults who have not responded to other treatments. Participants receive implanted electrodes that deliver mild electrical pulses to the lateral habenula. The main goal is to see if at least half of the patients show significant mood improvement after 6 months.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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