Brain pacemaker tested in older Parkinson's patients

NCT ID NCT03128567

Completed Disease control Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial investigates whether deep brain stimulation of the subthalamic nucleus can improve quality of life for people aged 70 and older with Parkinson's disease. Participants are randomly assigned to receive the stimulation or standard care. The study measures changes in motor symptoms, cognitive function, and overall well-being using a Parkinson's-specific quality-of-life questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep brain stimulation of the subthalamic nucleus (a device that sends electrical pulses to a specific brain area)
What this could lead to: If successful, this could show that deep brain stimulation is a safe and effective option for older adults with Parkinson's, improving their daily life and mobility.
What could go wrong: This is a small, early-stage trial with only 10 participants, so results may not apply to everyone. There is a risk of side effects like cognitive decline or falls in older patients.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

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Locations

CHU Charles Nicolle

Rouen, 76000, France
Centre d'Investigation Clinique - CIC 1436. CHU PURPAN. Hôpital Pierre Paul Riquet

Toulouse, 31059 Toulouse Cedex 9, France
Département des maladies du Système Nerveux, Hôpital Pitié-Salpétrière

Paris, 75013, France
Hôpital Neurologique Pierre Wertheimer, Service de Neurologie

Lyon, 69677 Bron cedex, France
Hôpital Roger Salengro - CHRU de Lille Service de Neurologie et Pathologie du Mouvement

Lille, 59037 Lille Cedex, France
Service d'EFSN, Hôpital Pellegrin

Bordeaux, 33076, France
Service de Neurologie, Pôle Neurosciences, CHU de Poitiers

Poitiers, 86021 Poitiers cedex, France

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