Brain pacemaker could curb alcohol cravings in severe addiction
NCT ID NCT07341230
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether deep brain stimulation (DBS) can safely reduce drinking in people with severe alcohol use disorder who haven't improved with standard treatments. DBS uses implanted electrodes to send small electrical signals to brain areas linked to craving and self-control. Nine adults will receive DBS and be monitored for changes in drinking habits and cravings over several months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Deep brain stimulation (DBS) device
- What this could lead to
- If it works, this could offer a new treatment option for people with severe alcohol addiction who haven't improved with standard therapies.
- What could go wrong
- This is a very small, early pilot study with only 9 participants, so results may not apply widely. DBS involves brain surgery, which carries risks like infection or bleeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cambridge University Hospitals (Addenbrooke's Hospital)
RECRUITINGCambridge, Cambridgeshire, CB2 0QQ, United Kingdom
Contact
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Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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King's College Hospital
RECRUITINGLondon, Greater London, SE5 9RS, United Kingdom
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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