Can plasma transfusion and blood filtering save lives in leptospirosis?
NCT ID NCT07127718
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether plasma transfusion and a blood-filtering procedure called hemoperfusion can prevent lung damage and death in people with leptospirosis, a bacterial infection spread by animals. Researchers will also check if a blood marker called CFI can predict who will get severe complications. About 678 participants will receive either standard care or one of the experimental treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Plasma transfusion and hemoperfusion
What this could lead to
If successful, this could provide new treatments to prevent severe lung damage and improve survival in leptospirosis patients.
What could go wrong
This is a Phase 2 trial, so the treatments are still experimental. They may not work better than standard care, and there are risks like allergic reactions or bleeding from plasma transfusion.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Institute of Human Genetics, National Institutes of Health - University of the Philippines Manila
ACTIVE_NOT_RECRUITINGManila, National Capital Region, 1000, Philippines
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National Kidney and Transplant Institute
RECRUITINGQuezon City, National Capital Region, 1100, Philippines
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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San Lazaro Hospital
RECRUITINGManila, National Capital Region, 1003, Philippines
Contact
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact