New shot aims to control prostate cancer by blocking testosterone

NCT ID NCT06395753

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 23 times

Summary

This study tests a new long-acting injection called Debio 4228 for men with advanced prostate cancer. The drug blocks a hormone that tells the body to make testosterone, which can fuel cancer growth. The goal is to find the right dose that safely lowers testosterone levels to slow the disease. About 66 men with advanced prostate cancer that needs ongoing hormone therapy will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AP Medical Research

    Miami, Florida, 33165, United States

  • AP-HP Hopital Pitie-Salpetriere

    Paris, 75013, France

  • AZ Groeninge

    Kortrijk, 8500, Belgium

  • Alarcon Urology Center

    Montebello, California, 90640, United States

  • Bakersfield Institute of Advanced Urology

    Bakersfield, California, 93301, United States

  • CHRU de Brest - Hopital Morvan

    Brest, 29200, France

  • CHU Angers

    Angers, 49933, France

  • CHU de Nantes - Hôtel Dieu

    Nantes, 44093, France

  • Carolina Urologic Research Center

    Myrtle Beach, South Carolina, 29572, United States

  • Centre Georges Francois Leclerc

    Dijon, 21000, France

  • Centre Jean Perrin

    Clermont-Ferrand, 63011, France

  • Corporacio Sanitaria Parc Tauli - Hospital de Sabadell

    Sabadell, 08208, Spain

  • East Valley Urology Center of Arizona

    Queen Creek, Arizona, 85140, United States

  • Grimaldi Urology

    Chula Vista, California, 91910, United States

  • Hospital Clinic Barcelona

    Barcelona, 8036, Spain

  • Hospital Clinico San Carlos

    Madroñera, 28040, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, 08035, Spain

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Instituto Valenciano de Oncologia

    Valencia, 46009, Spain

  • Oregon Urology Institut

    Springfield, Oregon, 97477, United States

  • Summit Cancer Centers of North Spokane

    Spokane, Washington, 99208, United States

  • Tower Urology,

    Los Angeles, California, 90048, United States

  • Urologic Surgeons of Arizona

    Mesa, Arizona, 85206, United States

  • Urology Center of Southern California

    Murrieta, California, 92563, United States

  • Urology of Virginia

    Virginia Beach, Virginia, 23462, United States

  • Valley Urology

    Fresno, California, 93722, United States

Conditions

Explore the condition pages connected to this study.