New shot could tame prostate cancer by blocking testosterone
NCT ID NCT06395753
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times
Summary
This study tests a new long-acting injection called Debio 4228 for men with advanced prostate cancer. The goal is to lower testosterone levels to control the cancer. About 55 men will receive different doses to find the best one. This is not a cure, but a way to manage the disease long-term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alarcon Urology Center
Montebello, California, 90640, United States
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Bakersfield Institute of Advanced Urology
Bakersfield, California, 93301, United States
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Biogenix Molecular
Miami, Florida, 33165, United States
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CHU de Nantes - Hôtel Dieu
Nantes, 44093, France
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Carolina Urologic Research Center
Myrtle Beach, South Carolina, 29572, United States
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Centre Georges Francois Leclerc
Dijon, 21000, France
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Centre Jean Perrin
Clermont-Ferrand, 63011, France
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East Valley Urology Center of Arizona
Queen Creek, Arizona, 85140, United States
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Grimaldi Urology
Chula Vista, California, 91910, United States
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Hospital Clinic Barcelona
Barcelona, 8036, Spain
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Hospital Clinico San Carlos
Madroñera, 28040, Spain
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Hospital Universitario Vall d'Hebron
Barcelona, 08035, Spain
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Instituto Valenciano de Oncologia
Valencia, 46009, Spain
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Oregon Urology Institut
Springfield, Oregon, 97477, United States
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Summit Cancer Centers of North Spokane
Spokane, Washington, 99208, United States
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Tower Urology,
Los Angeles, California, 90048, United States
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Urologic Surgeons of Arizona
Mesa, Arizona, 85206, United States
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Urology Center of Southern California
Murrieta, California, 92563, United States
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Urology of Virginia
Virginia Beach, Virginia, 23462, United States
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Valley Urology
Fresno, California, 93722, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new tracer light up hidden prostate cancer?
- Could deep breaths before surgery ward off Post-Op confusion?
- Can a new injection tame prostate cancer by cutting testosterone?
- A second look: MRI screening may spot hidden prostate cancers
- Can precision protons spare the bowel in prostate cancer?
- AI coaches doctors on cancer risk talks